(CNN) More bad news for diet soda lovers: Drinking two or more of any kind of artificially sweetened drinks a day is linked to an increased risk of clot-based strokes, heart attacks and early death in women over 50, according to a new study by the American Heart Association and American Stroke Association.

The risks were highest for women with no history of heart disease or diabetes and women who were obese or African-American.

Previous research has shown a link between diet beverages and stroke, dementiaType 2 diabetesobesity and metabolic syndrome, which can lead to heart disease and diabetes.

“This is another confirmatory study showing a relationship between artificially sweetened beverages and vascular risks. While we cannot show causation, this is a yellow flag to pay attention to these findings,” said American Academy of Neurology President Dr. Ralph Sacco, who was not involved in the latest study.

“What is it about these diet drinks?” asked lead study author Yasmin Mossavar-Rahmani, an associate professor of clinical epidemiology and population health at the Albert Einstein College of Medicine in the Bronx, New York. “Is it something about the sweeteners? Are they doing something to our gut health and metabolism? These are questions we need answered.”

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